THE ASSOCIATIONS BETWEEN COPING RESOURCES AND HELP-SEEKING INTENTION IN A SAMPLE OF CHINESE FIRST-YEAR MEDICAL STUDENTS: MEDIATION EFFECTS OF COPING STRATEGIES

The associations between coping resources and help-seeking intention in a sample of Chinese first-year medical students: mediation effects of coping strategies

Abstract Background Help-seeking is an adaptive coping process encompassing orientation, intention and actual behaviors.Help-seeking intention which promotes help-seeking behavior is a protective factor for mental health.However, the psychological paths for help-seeking intention in first-year medical students, a population vulnerable to mental hea

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Structural basis of Rap phosphatase inhibition by Phr peptides.

Two-component systems, composed of a sensor histidine kinase and an effector response regulator (RR), viqua-f4 are the main signal transduction devices in bacteria.In Bacillus, the Rap protein family modulates complex signaling processes mediated by two-component systems, such as competence, sporulation, or biofilm formation, by inhibiting the RR c

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RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination

Abstract RNF2 is a RING domain-containing E3 ubiquitin ligase that mediate histone H2A mono-ubiquitination 6-0 igora vibrance to repress gene transcription, but its expression patterns and molecular function in hepatocellular carcinoma (HCC) remain unclear.Herein, we extracted data from TGCA database and validated RNF2 expression in our own cohort,

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